¹³C Immobilized Reagent

Novel liquid reagent which is easy to handle and to control the reaction equivalent

Overview

　Carboxylic acid compounds containing aromatic rings are important molecular structures as bioactive compounds and their precursors. For example, aromatic carboxylic acids such as aspirin and telmisartan and aromatic ring-containing carboxylic acids such as atorvastatin are known as important drugs. Therefore, it is desired to develop carboxylation reactions of organic molecules that can efficiently synthesize aromatic carboxylic acid compounds.
　On the other hand, introduction of the ¹²C isotope ¹³C into organic molecules is important for elucidating the mechanism of chemical reactions or monitoring in vivo. For the conventional method, ¹³CO₂ gas is reacted as the ¹³C source, but special equipment and technology are required, and thus it is difficult to accurately control the amount of the gas.
　This invention provides to a novel ¹³Cimmobilizer in a liquid form that is easy to handle.

Since this patent application has not been published, the structural formula of the compound has not been disclosed. Please feel free to contact us as we can disclose this after signing a non-disclosure agreement.

Features・Outstandings

Product Application

・¹³C label introducer, immobilized reagent

IP Data

IP No.　 ： PCT/JP2024/039287　　　
Inventor ： SHIGENO Masanori, SASAMOTO Ozora, SHIMOTAI Kanta
keyword ： ¹³C, C isotope, label introducer, immobilization reagent